In several test series and repetitions, we have the foods green tea, aronia juice, pomegranate juice and elderberry juice as well as several recipes of lozenges developed by us with extracts from foods and medicinal plants in-vitro Have tested against the current corona virus, the "swine flu" virus and other viruses.
The results are very promising with regard to the possible reduction in the spread of the virus among people and to alleviate the severity of the course of infection. Human studies are intended.
Antiviral activity of plant juices, green tea and lozenges against SARS-CoV-2 and influenza virus - results of in-vitro studies and plausible applications
To assess the virucidal potential, the virologists commissioned carried out a quantitative suspension test with a modified vaccinia virus (MVA). MVA is a resilient surrogate virus that is used to validate virucidal disinfectants against all enveloped viruses in accordance with the European Guideline on Biocidal Products. While no reduction in the virus titer was observed during the incubation with control buffer, a 5-minute incubation with aronia, elderberry, pomegranate juice or green tea (Figure 1) or various recipes of lozenges (Figure 2) resulted in a decrease in infectivity, which indicates that the products tested are generally active against enveloped viruses. Furthermore, the two respiratory, enveloped viruses that were responsible for the "swine flu" 2009/2010, an influenza A virus (IAV) and the ongoing pandemic COVID-19, SARS-CoV-2, as well as an adenovirus (AdV5) were examined. as an unenveloped sample virus. The flu virus was most susceptible to all products, and all products tested reduced infectivity by> 99%. The SARS-CoV-2 titers were reduced by about 80% after 1 minute of incubation with pomegranate juice and green tea, but not influenced by elderberry juice, which roughly corresponds to the results obtained with the more resistant surrogate virus MVA . The naked AdV5 was largely resistant to most of the products tested. As expected, the tested lozenges also showed very good effects against the influenza virus and significantly different effects against the SARS-CoV-2 virus. The results indicate that the products tested are generally active against enveloped viruses.
Figure 2: Virucidal activity of lozenges against MVA, SARS-CoV-2, IAV, AdV5. MVA: Modified Vaccinia Virus Ankara, SARS-CoV-2: current corona virus, IAV: "Swine Flu" Virus (2009), AdV5: Before the serial titration and inoculation of the target cells, adenovirus adenoid 75 were incubated with the lozenges dissolved in water (1 lozenge in 25 ml water) for the contact times indicated.